Antidepressants Failed to Prevent Many Suicides, Used in Many Overdose Deaths, Study of Inquests Reveals

A recent study of coroner inquests revealed that about half of the deaths of people using antidepressants were determined to be suicides, indicating the drugs were not effective in preventing those deaths.

Brain image

A landmark 2022 study found that the common reason given for taking antidepressants – to correct a chemical imbalance in the brain – had no scientific basis.

CCHR recommends a complete physical examination with lab tests, nutritional and allergy screenings, and a review of all current medications to identify any physical causes of depression, which might otherwise be incorrectly diagnosed as a psychiatric disorder.

New study is latest to question current high rates of antidepressant prescribing in light of growing evidence of the drugs’ ineffectiveness and risks of harm.

Doctors…have an ethical responsibility to avoid prescribing or recommending treatments…which increase suicidality in many, and which constitute an effective method for killing oneself.”

— John Read, PhD, professor of psychology at the University of East London

WASHINGTON, DC, US, May 4, 2023/EINPresswire.com/ — An examination of coroner inquests revealed that about half of the deaths of people who used antidepressants were determined to be suicides. One in eight of the deaths involved an overdose of antidepressants. The new study offers evidence of the failure of antidepressants to prevent many suicides, as well as their use to commit suicide through overdose.

The study relied on 7,829 media reports of coroner inquests in England and Wales from 2003 to 2020 in which antidepressants had been used by the deceased. Coroners determined that 3,543, or nearly half (45%), of the deaths were suicides. The antidepressants most frequently taken by the deceased users were newer generation selective serotonin reuptake inhibitors, or SSRIs, (49%) and tricyclics (25%), an earlier type of antidepressant.

Of the 2,329 cases of overdose deaths by antidepressant users, 933 (40%) overdosed on their antidepressants, half (55%) of them with no other substances involved.

“If preventing suicide is a primary reason for prescribing ADs [antidepressants], this data set includes several thousand people for whom the drugs clearly did not work,” according to study author John Read, PhD, professor of psychology at the University of East London, writing in the peer-reviewed journal Ethical Human Psychology and Psychiatry. “Furthermore, about 1,000 people used the drugs that were supposed to alleviate their depression to kill themselves [by overdosing].”

In another 929 overdose cases, it could not be determined from media reports whether the substance used was an antidepressant, but some of them could have been. “So in somewhere between 40.1% and 80.0% of the overdoses, the medicines prescribed to help prevent suicide were used to commit suicide,” Read observed.

While there is no way of knowing the exact extent to which either the antidepressants or the individuals’ problems contributed to taking their own lives, the antidepressants failed to provide enough relief from their depression to prevent the suicides, according to Read.

“In none of the 3,543 cases of which the coroner reached a clear ‘suicide’ verdict, can ADs [antidepressants] be reasonably described as effective,” he wrote.

The study points out that many media reports of inquests did not include any information about the results of toxicology tests, or used phrases like “got help for depression” but did not explicitly state that antidepressants were used. “So ‘tip of the iceberg’ seems an accurate description of the data set” available for the study, Read noted, suggesting that suicides and overdose deaths among antidepressant users are likely substantially understated.

“Doctors…have an ethical responsibility to avoid prescribing or recommending treatments…which increase suicidality in many, and which constitute an effective method for killing oneself,” Read wrote in conclusion.

Some 45 million Americans are currently taking one or more antidepressants, including 5.7 million children and young adults under the age of 25, for whom the FDA requires a warning on the drug’s package insert of the increased risk of suicidal thoughts and actions.

A landmark 2022 study questioned the prescribing of antidepressants after finding the common reason for taking them – to correct a chemical imbalance in the brain – had no scientific basis. The study investigated whether evidence supported the theory that a low level of the brain chemical serotonin causes depression.

“The serotonin theory of depression has been one of the most influential and extensively researched biological theories of the origins of depression,” the researchers wrote. “Our study shows that this view is not supported by scientific evidence. It also calls into question the basis for the use of antidepressants.”

Prescribing antidepressants for depression was challenged in another 2022 study which found no clinically significant difference in measures of depression symptoms between adults treated with antidepressants and those taking placebos, whether over a shorter or longer time frame and regardless of the depression severity of the study participants.

Still another study indicated that taking antidepressants led to worse depression symptoms later in life. Researchers found that those who used antidepressants anytime during the 30-year period of the study had an 81% greater chance of having more severe depression symptoms at the end of the study. [1]

Antidepressants also carry the risks of adverse effects that include weight gain, nausea, insomnia, agitation, emotional blunting and sexual dysfunction. A 2020 study found that half of antidepressant users experience sexual problems from taking the drugs, which can strain their relationships and lead to worsening depression. [2]

In a 2017 survey, 44% of antidepressant users reported the drugs negatively impacted their sex lives, 27% their ability to work or study, and 21% their relationships with friends or family. [3]

Discontinuing antidepressants can bring on still other symptoms during withdrawal, including electric shock-like sensations (“brain zaps” and “body zaps”), muscle spasms and tremors, hallucinations, confusion, irritability, and mania. A 2019 study found that more than half (56%) of people attempting to come off antidepressants experience withdrawal symptoms, with nearly half (46%) of them describing those symptoms as severe, and that the symptoms can last for weeks or months. [4]

WARNING: Anyone wishing to discontinue or change the dose of an antidepressant or other psychiatric drug is cautioned to do so only under the supervision of a physician because of potentially dangerous withdrawal symptoms.

The Citizens Commission on Human Rights (CCHR) continues to raise public awareness of the risks of serious side effects and withdrawal symptoms from antidepressants and other psychiatric drugs, so that consumers and their physicians can make fully informed decisions about starting or stopping the drugs. CCHR supports safe and science-based non-drug approaches to mental health.

CCHR also recommends a complete physical examination with lab tests, nutritional and allergy screenings, and a review of all current medications to identify any physical causes of depression or other unwanted mental and behavioral symptoms, which might otherwise be misdiagnosed and incorrectly treated as a psychiatric disorder.

The Citizens Commission on Human Rights was co-founded in 1969 by members of the Church of Scientology and the late psychiatrist and humanitarian Thomas Szasz, M.D., recognized by many academics as modern psychiatry’s most authoritative critic, to eradicate abuses and restore human rights and dignity to the field of mental health. CCHR has been instrumental in obtaining 228 laws against psychiatric abuse and violations of human rights worldwide.

The CCHR National Affairs Office in Washington, DC, has advocated for mental health rights and protections at the state and federal level. The CCHR traveling exhibit, which has toured 441 major cities worldwide and educated over 800,000 people on the history to the present day of abusive and racist psychiatric practices, has been displayed at the Congressional Black Caucus Foundation Annual Legislative Conference in Washington, DC, and at other locations.

[1] https://pubmed.ncbi.nlm.nih.gov/29680831

[2] https://www.sciencedirect.com/science/article/pii/S0941950019301708

[3] https://www.sciencedirect.com/science/article/abs/pii/S0165178117305371

[4] https://www.sciencedirect.com/science/article/pii/S0306460318308347?via%3Dihub

Anne Goedeke
Citizens Commission on Human Rights, National Affairs Office
+1 202-349-9267
email us here
Visit us on social media:
Facebook

CCHR: Antidepressant warning



Originally published at https://www.einpresswire.com/article/631677538/antidepressants-failed-to-prevent-many-suicides-used-in-many-overdose-deaths-study-of-inquests-reveals